Aman U Buzdar Selected Research

Cyclophosphamide (Cytoxan)

1/2022	Molecular Characterization and Prospective Evaluation of Pathologic Response and Outcomes with Neoadjuvant Therapy in Metaplastic Triple-Negative Breast Cancer.
12/2013	Fluorouracil, epirubicin, and cyclophosphamide (FEC-75) followed by paclitaxel plus trastuzumab versus paclitaxel plus trastuzumab followed by FEC-75 plus trastuzumab as neoadjuvant treatment for patients with HER2-positive breast cancer (Z1041): a randomised, controlled, phase 3 trial.
3/2012	Phase III trial evaluating weekly paclitaxel versus docetaxel in combination with capecitabine in operable breast cancer.
7/2011	Prospective randomized trial of 5-fluorouracil, doxorubicin, and cyclophosphamide (FAC) versus paclitaxel and FAC (TFAC) in patients with operable breast cancer: impact of taxane chemotherapy on locoregional control.
1/2011	Phase III randomized trial of dose intensive neoadjuvant chemotherapy with or without G-CSF in locally advanced breast cancer: long-term results.
7/2010	Acute and late onset cognitive dysfunction associated with chemotherapy in women with breast cancer.
2/2010	A phase II neoadjuvant trial of sequential nanoparticle albumin-bound paclitaxel followed by 5-fluorouracil/epirubicin/cyclophosphamide in locally advanced breast cancer.
9/2007	Efficacy and safety of neoadjuvant trastuzumab combined with paclitaxel and epirubicin: a retrospective review of the M. D. Anderson experience.
1/2007	CD40 signaling predicts response to preoperative trastuzumab and concomitant paclitaxel followed by 5-fluorouracil, epirubicin, and cyclophosphamide in HER-2-overexpressing breast cancer.
1/2007	Neoadjuvant therapy with paclitaxel followed by 5-fluorouracil, epirubicin, and cyclophosphamide chemotherapy and concurrent trastuzumab in human epidermal growth factor receptor 2-positive operable breast cancer: an update of the initial randomized study population and data of additional patients treated with the same regimen.

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Aman U Buzdar Research Topics

Disease

146	Breast Neoplasms (Breast Cancer) 01/2022 - 01/2002
56	Neoplasms (Cancer) 01/2022 - 01/2002
18	Pathologic Complete Response 01/2022 - 06/2005
7	Neoplasm Metastasis (Metastasis) 06/2010 - 08/2002
6	Residual Neoplasm 04/2017 - 04/2004
5	Endometrial Neoplasms (Endometrial Cancer) 02/2008 - 12/2002
4	Disease Progression 01/2018 - 05/2004
4	Uterine Hemorrhage (Uterine Bleeding) 02/2008 - 12/2002
3	Lymphatic Metastasis 05/2012 - 03/2006
3	Cardiotoxicity 09/2007 - 11/2002
3	Carcinoma (Carcinomatosis) 02/2006 - 04/2004
2	Triple Negative Breast Neoplasms 01/2022 - 05/2013
2	Exanthema (Rash) 04/2015 - 01/2013
2	Febrile Neutropenia 01/2011 - 02/2010
2	Noninfiltrating Intraductal Carcinoma (DCIS) 01/2011 - 01/2007
2	Cognitive Dysfunction 07/2010 - 08/2004
2	Obesity 09/2008 - 09/2008
2	Lobular Carcinoma 11/2006 - 01/2005
2	Inflammatory Breast Neoplasms 03/2006 - 02/2004
2	Male Breast Neoplasms (Male Breast Cancer) 12/2005 - 06/2002
2	Heart Failure 06/2005 - 11/2002
1	Overweight 01/2016
1	Pain (Aches) 04/2015
1	Digestive System Diseases 01/2013
1	Anemia 07/2011
1	Infections 01/2011
1	Thrombocytopenia (Thrombopenia) 01/2011
1	Myalgia 02/2010
1	Arthralgia (Joint Pain) 09/2008
1	Arthritis (Polyarthritis) 09/2008
1	Osteoporosis 07/2008

Drug/Important Bio-Agent (IBA)

33	Tamoxifen FDA LinkGeneric 05/2013 - 01/2002
31	Estrogen ReceptorsIBA 01/2019 - 01/2002
28	Anastrozole (Arimidex)FDA LinkGeneric 01/2021 - 06/2002
28	Hormones (Hormone)IBA 04/2015 - 10/2002
27	Aromatase InhibitorsIBA 01/2020 - 11/2002
22	Cyclophosphamide (Cytoxan)FDA LinkGeneric 01/2022 - 01/2002
21	Paclitaxel (Taxol)FDA LinkGeneric 12/2013 - 04/2002
20	Fluorouracil (Carac)FDA LinkGeneric 12/2013 - 01/2002
19	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2022 - 01/2002
16	Trastuzumab (Herceptin)FDA Link 03/2016 - 06/2005
12	Letrozole (Femara)FDA LinkGeneric 05/2007 - 11/2002
11	Progesterone Receptors (Progesterone Receptor)IBA 05/2013 - 10/2002
11	AnthracyclinesIBA 05/2012 - 05/2002
9	exemestane (Aromasin)FDA Link 01/2020 - 01/2003
8	Estrogens (Estrogen)FDA Link 01/2021 - 12/2002
8	human ERBB2 proteinIBA 04/2017 - 06/2005
7	Epirubicin (Ellence)FDA LinkGeneric 12/2013 - 06/2005
6	Biomarkers (Surrogate Marker)IBA 01/2021 - 02/2008
6	Fulvestrant (Faslodex)FDA Link 01/2020 - 01/2003
5	taxaneIBA 07/2011 - 10/2004
5	Megestrol Acetate (Borea)FDA LinkGeneric 01/2004 - 11/2002
4	ErbB Receptors (EGF Receptor)IBA 04/2015 - 10/2002
4	Taxoids (Taxanes)IBA 12/2009 - 01/2003
3	Aromatase (CYP19)IBA 07/2017 - 12/2002
3	Lapatinib (GW572016)FDA Link 03/2016 - 01/2013
3	Selective Estrogen Receptor Modulators (SERM)IBA 09/2013 - 07/2008
3	Estrogen Receptor AntagonistsIBA 09/2008 - 01/2003
3	Estrogen Receptor Modulators (Antiestrogen)IBA 02/2006 - 01/2003
2	DNA (Deoxyribonucleic Acid)IBA 04/2013 - 03/2011
2	Docetaxel (Taxotere)FDA Link 05/2012 - 03/2012
2	Capecitabine (Xeloda)FDA Link 03/2012 - 03/2008
2	Messenger RNA (mRNA)IBA 11/2011 - 01/2007
2	Proteins (Proteins, Gene)FDA Link 10/2010 - 09/2004
2	Tumor Biomarkers (Tumor Markers)IBA 10/2010 - 01/2008
2	LY 353381 (LY353381)IBA 07/2008 - 11/2007
2	Epothilones (Epothilone)IBA 03/2008 - 12/2007
2	thiamine triphosphorate (TTP)IBA 09/2004 - 05/2004
1	tipifarnib (R115777)IBA 01/2018
1	Gemcitabine FDA Link 01/2018
1	Estrone FDA Link 07/2017
1	Androstenedione (4 Androstene 3,17 dione)IBA 07/2017
1	TOR Serine-Threonine KinasesIBA 05/2013
1	Epidermal Growth Factor (EGF)IBA 05/2013
1	Poly(ADP-ribose) Polymerase InhibitorsIBA 05/2013
1	Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA 05/2013
1	Estradiol (Delestrogen)FDA LinkGeneric 04/2013
1	N 30IBA 05/2012
1	RNA-Directed DNA Polymerase (Reverse Transcriptase)IBA 05/2012
1	MicroRNAs (MicroRNA)IBA 05/2012
1	Carboplatin (JM8)FDA LinkGeneric 05/2012
1	HematinicsIBA 07/2011
1	Granulocyte Colony-Stimulating Factor (G-CSF)IBA 01/2011
1	Blood Proteins (Serum Proteins)IBA 10/2010
1	Albumin-Bound Paclitaxel FDA Link 02/2010
1	Growth Factor ReceptorsIBA 09/2008
1	LipidsIBA 07/2008
1	desoxyepothilone B (epothilone D)IBA 03/2008
1	ixabepilone (BMS 247550)FDA Link 03/2008

Therapy/Procedure

56	Therapeutics 01/2019 - 01/2002
52	Drug Therapy (Chemotherapy) 01/2019 - 01/2002
34	Neoadjuvant Therapy 01/2022 - 01/2002
10	Adjuvant Chemotherapy 01/2013 - 01/2002
9	Radiotherapy 01/2007 - 07/2002
8	Mastectomy (Mammectomy) 07/2006 - 01/2002
4	Segmental Mastectomy (Lumpectomy) 03/2011 - 04/2002
2	Aftercare (After-Treatment) 10/2004 - 02/2004
1	Withholding Treatment 07/2010
1	Lymph Node Excision (Lymph Node Dissection) 06/2010
1	Combined Modality Therapy 12/2008